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Statins as neuroprotectants: a comparative in vitro study of lipophilicity, blood-brain-barrier penetration, lowering of brain cholesterol, and decrease of neuron.

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Sep 7, - However, the effects of statins of differing blood-brain barrier (BBB) as a function of BBB penetration, cerebrospinal fluid (CSF) and plasma.

Feb 27, - In order for atorvastatin to be able to effect Aβ formation in the brain and attenuate damage from neuroinflammation it must be able to be lipophilic to cross the blood brain barrier.

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